Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084103 | 1.00 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL30084108 | 1.00 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL8159372 | 0.84 | LMNA (0.47) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL29246850 | 0.84 | LMNA (0.47) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL8159369 | 0.84 | LMNA (0.47) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL8081928 | 0.84 | LMNA (0.47) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL11403725 | 0.80 | — | — | |
| SCHEMBL10991428 | 0.79 | LMNA (0.43) | LMNAALDH1A1TP53CACNA1CL3MBTL1 | |
| SCHEMBL11052010 | 0.79 | LMNA (0.49) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL30084112 | 0.76 | MAPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52083720-A | — | — | None | — | — | JP | disclosed |
| EP-0343812-B1 | PROCESS FOR PREPARING TRANS-2,2-DIMETHYL-3-(2,2-DIHALOVINYL)-CYCLOPROPANE CARBOXYLIC ACID ESTERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4948914-A | Process for preparing trans-2,2-dimethyl-3-(2,2-dihalovinyl)cyclopropane carboxylic acid esters | SUMITOMO CHEMICAL CO., LIMITED (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0343812-A1 | Process for preparing trans-2,2-dimethyl-3-(2,2-dihalovinyl)-cyclopropane carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-29 | — | — | EP | disclosed |
| US-4250326-A | Method of reducing the contents of haloethynyl-containing impurities in synthetic dihaloethenyl pyrethroid insecticides or intermediates by reaction with phosphites | FMC CORPORATION (US) | 1981-02-10 | — | — | US | disclosed |
| US-4166064-A | 4,6,6,6 -TETRACHLORO-3,3-DIMETHYLHEXANOATE, ALKALI METAL TERT-ALKOXIDE | FMC CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
| JP-S5283720-A | SUBSTITUTED CYCLOPROPANECARBOXYLIC ACID DERIVATIVES, AND INSECTICIDES AND ACARICIDES CONTAINING A-SUBSTITUTED CYCLOPROPANECARBOXYLIC ACID DERI VATIVES | KURARAY CO LTD | 1977-07-12 | — | — | JP | disclosed |