Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153731 | 0.81 | KMT2A (0.60) | KMT2AL3MBTL1POLBMEN1LMNA | |
| SCHEMBL22453573 | 0.81 | KMT2A (0.58) | KMT2AL3MBTL1POLBMEN1LMNA | |
| SCHEMBL30194821 | 0.79 | MAPT (0.54) | POLBLMNAKDM4EGAACA12 | |
| SCHEMBL10984838 | 0.78 | MAPT (0.64) | KMT2AL3MBTL1POLBMEN1LMNA | |
| SCHEMBL10716542 | 0.76 | KMT2A (0.66) | KMT2AL3MBTL1POLBMEN1LMNA | |
| SCHEMBL11386499 | 0.75 | L3MBTL1 (0.75) | KMT2AL3MBTL1POLBMEN1LMNA | |
| SCHEMBL20988227 | 0.74 | MAPT (0.61) | LMNAKIF11 | |
| SCHEMBL19808846 | 0.74 | LMNA (0.60) | KMT2AL3MBTL1POLBMEN1LMNA | |
| SCHEMBL5293398 | 0.74 | KMT2A (0.47) | KMT2APOLBMEN1LMNASMN1; SMN2 | |
| SCHEMBL16479498 | 0.73 | MAPT (0.64) | KMT2AL3MBTL1POLBMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |