SCHEMBL815952

SCHEMBL815952

C=CC(=O)OCCOc1ccc(-c2ccc(OCC3CCC(COC)CC3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
PARP15 Q460N3 4/20 0.43
PARP10 Q53GL7 4/20 0.43
PARP2 Q9UGN5 2/20 0.43
HPGD P15428 1/20 0.38
ACACB O00763 4/20 0.37
ACACA Q13085 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
BTK Q06187 1/20 0.36
RARB P10826 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13040997 0.89 THRB (0.53) THRBPARP15PARP10PARP2HPGD
SCHEMBL816442 0.84 PARP15 (0.45) THRBPARP15PARP10PARP2HPGD
SCHEMBL816455 0.83 PARP15 (0.50) THRBPARP15PARP10PARP2HPGD
SCHEMBL9418508 0.82 THRB (0.75) THRBHPGDRARB
SCHEMBL815784 0.82 PARP15 (0.43) THRBPARP15PARP10PARP2HPGD
SCHEMBL12604094 0.81 THRB (0.65) THRBHPGDTDP1
SCHEMBL21982971 0.79 THRB (0.41) THRBPARP15PARP10PARP2HPGD
SCHEMBL22995854 0.78 THRB (0.65) THRBHPGDFFAR4
SCHEMBL17716764 0.78 THRB (0.69) THRBHPGDRARB
SCHEMBL24804854 0.78 THRB (0.69) THRBHPGDRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2261201-B1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND DAINIPPON INK & CHEMICALS (JP) 2018-05-30 EP disclosed
US-8057701-B2 Trifunctional (meth)acrylate compound and polymerizable composition containing same ADEKA CORPORATION (JP) 2011-11-15 US disclosed
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2011-02-17 US disclosed
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2011-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110037025-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME PYM1, MT-CO1, MAT1A THRB 341/4885PARP15 2023/4885PARP10 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.