Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159975 | 1.00 | TBXAS1 (0.71) | TBXAS1AKR1C3LMNANPC1ALDH1A1 | |
| SCHEMBL7764218 | 0.94 | TBXAS1 (0.68) | TBXAS1AKR1C3LMNANPC1ALDH1A1 | |
| SCHEMBL7764222 | 0.94 | TBXAS1 (0.68) | TBXAS1AKR1C3LMNANPC1ALDH1A1 | |
| SCHEMBL29158024 | 0.86 | TBXAS1 (0.56) | TBXAS1AKR1C3LMNANPC1ALDH1A1 | |
| SCHEMBL7284398 | 0.85 | TBXAS1 (0.97) | TBXAS1 | |
| SCHEMBL7284401 | 0.85 | TBXAS1 (0.97) | TBXAS1 | |
| SCHEMBL11061432 | 0.85 | TBXAS1 (0.70) | TBXAS1AKR1C3 | |
| SCHEMBL11061416 | 0.85 | TBXAS1 (0.70) | TBXAS1AKR1C3 | |
| SCHEMBL7766698 | 0.84 | AKR1C3 (0.57) | TBXAS1AKR1C3LMNANPC1ALDH1A1 | |
| SCHEMBL7766699 | 0.84 | AKR1C3 (0.57) | TBXAS1AKR1C3LMNANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001652-A1 | NEW INDANONE DERIVATIVES AND METHOD FOR PRODUCING SAME | RIEGER BERNHARD (DE) | 2000-01-13 | — | — | WO | disclosed |