SCHEMBL29158024

SCHEMBL29158024

CC(=Cc1ccc(Cc2ccccc2)cc1)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 7/20 0.56
PLA2G10 O15496 1/20 0.51
PLA2G2A P14555 1/20 0.51
LMNA P02545 1/20 0.51
AKR1C3 P42330 1/20 0.50
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
SLC22A2 O15244 1/20 0.42
EGFR P00533 1/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
MCL1 Q07820 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
CALM1 P0DP23 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8159971 0.86 TBXAS1 (0.71) TBXAS1PLA2G10PLA2G2ALMNAAKR1C3
SCHEMBL8159975 0.86 TBXAS1 (0.71) TBXAS1PLA2G10PLA2G2ALMNAAKR1C3
SCHEMBL554744 0.84 AKR1C3 (0.69) AKR1C3NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL476911 0.84 AKR1C3 (0.69) AKR1C3NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL5830531 0.82 AKR1C3 (0.52) AKR1C3NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL5830527 0.82 AKR1C3 (0.52) AKR1C3NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL6930239 0.81 NOS3 (0.43) TBXAS1AKR1C3NPC1RAB9AALDH1A1
SCHEMBL7764218 0.80 TBXAS1 (0.68) TBXAS1LMNAAKR1C3NPC1RAB9A
SCHEMBL7764222 0.80 TBXAS1 (0.68) TBXAS1LMNAAKR1C3NPC1RAB9A
Phenol SCHEMBL29181787 0.77 AKR1C3 (0.60) AKR1C3NPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117597372-A Novel (meth) acrylamide polymer, resin composition containing the same, and molded article thereof 日本曹达株式会社 2024-02-23 CN disclosed