Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446252 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAOBTSHRCYP2A6LMNA | |
| SCHEMBL398575 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAOBTSHRCYP2A6LMNA | |
| SCHEMBL5098432 | 0.69 | — | — | |
| SCHEMBL8164 | 0.67 | — | — | |
| SCHEMBL8851768 | 0.67 | — | — | |
| SCHEMBL4159814 | 0.67 | — | — | |
| SCHEMBL176876 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28457481 | 0.65 | ALDH1A1 (0.45) | ALDH1A1MAOBTSHRCYP2A6LMNA | |
| SCHEMBL2686341 | 0.65 | ALDH1A1 (0.52) | ALDH1A1MAOBTSHRCYP2A6LMNA | |
| SCHEMBL21379865 | 0.64 | POLB (0.41) | ALDH1A1TSHRLMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037452-A | Poly(alkylene oxide)-Factor VIII or Factor IX conjugate | ALPHA THERAPEUTIC CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| WO-1993000109-A1 | METHOD OF STIMULATING IMMUNE RESPONSE USING GROWTH HORMONE | GENENTECH, INC. (US) | 1993-01-07 | — | — | WO | disclosed |
| US-4179337-A | POLYALKYLENE GLYCOL LINKED TO POLYPEPTIDE THROUGH COUPLER | RESEARCH CORPORATION TECHNOLOGIES, INC., A NOT-FOR-PROFIT, NON-STOCK CORP. OF DE | 1979-12-18 | — | — | US | disclosed |