SCHEMBL446252

SCHEMBL446252

[CH](N[CH]c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAOB P27338 2/20 0.45
TSHR P16473 2/20 0.45
CYP2A6 P11509 1/20 0.45
LMNA P02545 4/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NOX1 Q9Y5S8 1/20 0.39
NFE2L2 Q16236 1/20 0.38
CYP19A1 P11511 1/20 0.38
MAOA P21397 1/20 0.38
TRPA1 O75762 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPK1 P28482 1/20 0.38
HDAC3 O15379 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
ALOX12 P18054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL398575 0.85 ALDH1A1 (0.52) ALDH1A1MAOBTSHRCYP2A6LMNA
SCHEMBL8159972 0.83 ALDH1A1 (0.38) ALDH1A1MAOBTSHRCYP2A6LMNA
SCHEMBL5098432 0.78
SCHEMBL4159814 0.75
SCHEMBL176876 0.75
SCHEMBL2686341 0.73 ALDH1A1 (0.52) ALDH1A1MAOBTSHRCYP2A6LMNA
(Z)-1,2-Diphenylethene SCHEMBL11703942 0.72 MAOB (0.69) ALDH1A1MAOBLMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL11602792 0.72 MAOB (0.69) ALDH1A1MAOBLMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL5588939 0.72 MAOB (0.69) ALDH1A1MAOBLMNANFE2L2CYP19A1
SCHEMBL11237250 0.69 ALDH1A1 (0.36) ALDH1A1MAOBTSHRCYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC BUCK INST RES AGING (US) 2024-07-04 US claimed
CN-115703806-B Phosphine ligand of pyrazole-amide framework, and preparation method and application thereof 香港理工大学深圳研究院 2024-05-14 CN claimed
CN-117990817-A Method for measuring impurity content in pharmaceutical intermediate acyl chloride iminodibenzyl by utilizing HPLC 江苏慈星药业有限公司 2024-05-07 CN claimed
CN-117903864-A High-performance special synthetic lubricating oil and preparation method thereof 哈尔滨紫杉油脂股份有限公司 2024-04-19 CN claimed
CN-117430553-A Synthesis method of iminodibenzyl 河北八亿时空药业有限公司 2024-01-23 CN claimed
CN-117377651-A Cationic lipid with side chain containing functional groups and application thereof 厦门赛诺邦格生物科技股份有限公司 2024-01-09 CN claimed
CN-116836117-A Iminodibenzyl cyclization process and iminodibenzyl preparation process 浙江华洲药业有限公司 2023-10-03 CN claimed
CN-115057817-B Production process of iminostilbene 浙江华洋药业有限公司 2023-09-08 CN claimed
US-20230279286-A1 PROPPANTS DERIVED FROM CROSSLINKING MIXED AROMATIC RESINS ExxonMobil Technology and Engineering Company (US) 2023-09-07 US claimed
WO-2023168192-A1 PROPPANTS DERIVED FROM CROSSLINKING MIXED AROMATIC RESINS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2023-09-07 WO claimed
EP-0570336-A2 Novel high temperature dehydration process for the production of 5H-dibenz(b,f)azepine CIBA-GEIGY AG (CH) 1993-11-18 EP claimed
US-5254522-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1993-10-19 US claimed
EP-0237952-B1 PROCESS FOR THE PREPARATION OF 5H-DIBENZO-(B, F)-AZEPINE ORION-YHTYMÄ OY FERMION (FI) 1991-10-30 EP claimed
EP-0453395-A1 Pressure sensitive recording material CIBA-GEIGY AG (CH) 1991-10-23 EP claimed
US-5034294-A Light sensitive multilayer element with electron donors and electron acceptors CANON KABUSHIKI KAISHA (JP) 1991-07-23 US claimed
EP-0158115-B1 PROCESS FOR THE PREPARATION OF IMINODIBENZYL CL PHARMA AKTIENGESELLSCHAFT (AT) 1989-05-31 EP claimed
EP-0237952-A1 Process for the preparation of 5H-Dibenzo-(b, f)-azepine ORION-YHTYMÄ OY FERMION (FI) 1987-09-23 EP claimed
EP-0158115-A2 Process for the preparation of iminodibenzyl CL PHARMA AKTIENGESELLSCHAFT (AT) 1985-10-16 EP claimed
US-4013639-A PREPARATION OF ASYMMETRIC IMINODIBENZYL COMPOUNDS Kitamura, Eiichi (JA) 1977-03-22 US claimed
US-3945941-A POLYETHYLENE OR POLYPROPYLENE STORAGETANK LINERS OXIRANE CORPORATION (US) 1976-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC DAGLA, DAGLB, MGLL ALDH1A1 978/4885MAOB 2579/4885TSHR 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.