Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | DNM1L | O00429 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 7/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154164 | 0.89 | AR (0.45) | SMN1; SMN2NPC1RAB9AFAAHDNM1L | |
| SCHEMBL1935260 | 0.85 | FAAH (0.48) | SMN1; SMN2NPC1RAB9AFAAHDNM1L | |
| Hydrochloric Acid SCHEMBL29565681 | 0.84 | FAAH (0.48) | SMN1; SMN2NPC1RAB9AFAAHDNM1L | |
| Hydrochloric Acid SCHEMBL1146413 | 0.84 | FAAH (0.48) | SMN1; SMN2NPC1RAB9AFAAHDNM1L | |
| SCHEMBL1937653 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AFAAHAR | |
| SCHEMBL22078049 | 0.74 | DNM1L (0.50) | SMN1; SMN2NPC1RAB9AFAAHDNM1L | |
| SCHEMBL1146740 | 0.74 | FAAH (0.49) | SMN1; SMN2NPC1RAB9AFAAHAR | |
| SCHEMBL22592645 | 0.72 | DNM1L (0.41) | SMN1; SMN2NPC1RAB9AFAAHDNM1L | |
| SCHEMBL3774648 | 0.71 | FAAH (0.62) | SMN1; SMN2NPC1RAB9AFAAHAR | |
| SCHEMBL22592719 | 0.71 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AFAAHDNM1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114054-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-09-25 | — | — | WO | disclosed |