Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935260 | 0.90 | FAAH (0.48) | SMN1; SMN2RAB9ANPC1FAAHCTSL | |
| Hydrochloric Acid SCHEMBL1146413 | 0.89 | FAAH (0.48) | SMN1; SMN2RAB9ANPC1FAAHCTSL | |
| Hydrochloric Acid SCHEMBL29565681 | 0.89 | FAAH (0.48) | SMN1; SMN2RAB9ANPC1FAAHCTSL | |
| SCHEMBL1146740 | 0.87 | FAAH (0.49) | SMN1; SMN2RAB9ANPC1FAAHCTSL | |
| SCHEMBL1936698 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1CTSLCTSS | |
| SCHEMBL7927071 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ANPC1FAAHCTSL | |
| SCHEMBL8160271 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1FAAHCTSL | |
| SCHEMBL23657807 | 0.75 | AR (0.55) | SMN1; SMN2RAB9ANPC1FAAHALDH1A1 | |
| SCHEMBL16658465 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL3774648 | 0.74 | FAAH (0.62) | SMN1; SMN2RAB9ANPC1FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331548-A1 | PROTEASE INHIBITORS | Medivir AB (SE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010034788-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-01 | — | — | WO | disclosed |