SCHEMBL816052

SCHEMBL816052

Cc1cccc(C2=C3C(=O)NC(c4cccc(C)c4)=C3C(=O)N2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FYN P06241 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
NOTUM Q6P988 1/20 0.44
PARP10 Q53GL7 1/20 0.43
PARP11 Q9NR21 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
XDH P47989 1/20 0.41
ACHE P22303 1/20 0.41
PGR P06401 1/20 0.41
CAMK2D Q13557 1/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
IDO1 P14902 1/20 0.40
METAP2 P50579 1/20 0.40
NR3C2 P08235 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
MAOB P27338 1/20 0.38
PIM1 P11309 1/20 0.38
PIM2 Q9P1W9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425028 0.95 NPC1 (0.43) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL815772 0.93 FYN (0.44) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL13363624 0.92 FYN (0.40) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL12640542 0.89 FYN (0.41) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL12577694 0.89 FYN (0.41) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL7750654 0.89 GSK3B (0.43) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12509873 0.87 BRD4 (0.40) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL13578990 0.87 CAMK2D (0.41) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL12425017 0.86 FYN (0.40) FYNCLK4DYRK1BNOTUMPARP10
SCHEMBL3729848 0.79 CAMK2D (0.44) FYNCLK4DYRK1BNOTUMPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1502932-B1 RESIN COMPOSITION SONY CORP (JP) 2012-07-11 EP claimed
EP-2261286-B1 Resin composition SONY CORP (JP) 2012-06-06 EP claimed
EP-2261286-A1 Resin composition Sony Corporation (JP) 2010-12-15 EP claimed
EP-1502932-A1 RESIN COMPOSITION Sony Corporation (JP) 2005-02-02 EP claimed
US-6248165-B1 ORGANIC RED PIGMENTS FOR CELLULOSES AND PLASTICS; INCORPORATING A THIRD COMPONENT OF A DIKETOPYRROLE OR QUINACRIDONE PIGMENT INTO THE CRYSTAL LATTICE OF THE MIXED CRYSTAL; COLORFASTNESS; WEATHERPROOFING CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-19 US claimed
JP-8020731-A None JP disclosed
EP-2199052-B1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORP (JP) 2014-01-22 EP disclosed
EP-1502932-B1 RESIN COMPOSITION SONY CORP (JP) 2012-07-11 EP disclosed
EP-2261286-B1 Resin composition SONY CORP (JP) 2012-06-06 EP disclosed
EP-2261286-B1 Resin composition SONY CORP (JP) 2012-06-06 EP disclosed
US-8062574-B2 Process for production of injection-molded article of polylactic acid resin KAO CORPORATION (JP) 2011-11-22 US disclosed
EP-2261286-A1 Resin composition Sony Corporation (JP) 2010-12-15 EP disclosed
EP-0654506-A2 Process for the manufacture of synergetic mixtures of pigments CIBA-GEIGY AG (CH) 1995-05-24 EP disclosed
EP-0133156-B1 1,4-DIKETOPYRROLO-(3,4-C) PYRROLES CIBA-GEIGY AG (CH) 1991-07-10 EP disclosed
EP-0256983-B1 Solid solutions of pyrrolo-[3,4-c]pyrroles CIBA-GEIGY AG (CH) 1989-09-27 EP disclosed
US-4783540-A Solid solutions of pyrrolo-(3,4-C)-pyrrols CIBA-GEIGY CORPORATION (US) 1988-11-08 US disclosed
EP-0256983-A1 Solid solutions of pyrrolo-[3,4-c]pyrroles CIBA-GEIGY AG (CH) 1988-02-24 EP disclosed
US-4666455-A Compositions pigmented with N-substituted 1,4-diketopyrrolo-[3,4-c]-pyrroles CIBA-GEIGY CORPORATION (US) 1987-05-19 US disclosed
US-4585878-A N-substituted 1,4-diketopyrrolo-[3,4-c]-pyrroles CIBA-GEIGY CORPORATION (US) 1986-04-29 US disclosed
EP-0133156-A2 1,4-Diketopyrrolo-(3,4-c) pyrroles CIBA-GEIGY AG (CH) 1985-02-13 EP disclosed