SCHEMBL815772

SCHEMBL815772

Cc1ccc(C2=C3C(=O)NC(c4cccc(C)c4)=C3C(=O)N2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FYN P06241 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
PARP10 Q53GL7 1/20 0.42
PARP11 Q9NR21 1/20 0.42
PTGS2 P35354 1/20 0.41
PGR P06401 1/20 0.40
NOTUM Q6P988 1/20 0.40
HPGD P15428 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAOB P27338 1/20 0.38
XDH P47989 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL816052 0.93 FYN (0.45) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12425028 0.92 NPC1 (0.43) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL7750654 0.89 GSK3B (0.43) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12577694 0.89 FYN (0.41) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12640542 0.89 FYN (0.41) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL12425017 0.86 FYN (0.40) FYNCLK4DYRK1BPARP10PARP11
SCHEMBL9833136 0.86 PTGS2 (0.47) PTGS2HPGDMAOBALDH1A1MAPT
SCHEMBL13336739 0.86 PGR (0.46) PGRMAPTMEN1KMT2A
SCHEMBL815442 0.86 PTGS2 (0.50) PTGS2NOTUMHPGDMAOBKDM4E
SCHEMBL13363624 0.85 FYN (0.40) FYNCLK4DYRK1BPARP10PARP11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1502932-B1 RESIN COMPOSITION SONY CORP (JP) 2012-07-11 EP claimed
EP-2261286-B1 Resin composition SONY CORP (JP) 2012-06-06 EP claimed
EP-2261286-A1 Resin composition Sony Corporation (JP) 2010-12-15 EP claimed
US-7790782-B2 Resin composition SONY CORPORATION (JP) 2010-09-07 US claimed
US-20060106130-A1 Resin composition Lerner, David, Littenberg, Krumholz & Mentlik, LLP 2006-05-18 US claimed
EP-1502932-A1 RESIN COMPOSITION Sony Corporation (JP) 2005-02-02 EP claimed
EP-2199052-B1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORP (JP) 2014-01-22 EP disclosed
EP-1502932-B1 RESIN COMPOSITION SONY CORP (JP) 2012-07-11 EP disclosed
EP-2261286-B1 Resin composition SONY CORP (JP) 2012-06-06 EP disclosed
US-8062574-B2 Process for production of injection-molded article of polylactic acid resin KAO CORPORATION (JP) 2011-11-22 US disclosed
EP-2261286-A1 Resin composition Sony Corporation (JP) 2010-12-15 EP disclosed
US-7790782-B2 Resin composition SONY CORPORATION (JP) 2010-09-07 US disclosed
US-20100201037-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORPORATION (JP) 2010-08-12 US disclosed
EP-2199052-A1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN Kao Corporation (JP) 2010-06-23 EP disclosed
US-20060106130-A1 Resin composition Lerner, David, Littenberg, Krumholz & Mentlik, LLP 2006-05-18 US disclosed
EP-1502932-A1 RESIN COMPOSITION Sony Corporation (JP) 2005-02-02 EP disclosed
EP-0630381-A4 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. 1995-01-04 EP disclosed
EP-0630381-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. ACAD OF SCIENCE CZECH REPUBLIC (CS) 1994-12-28 EP disclosed