Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CEL | P19835 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152251 | 0.83 | TAAR1 (0.50) | GAAHTTCELKDM4EELANE | |
| SCHEMBL7688328 | 0.74 | ACHE (0.50) | LMNAGAAMAPTTSHRHTT | |
| SCHEMBL13475568 | 0.73 | HPGD (0.51) | LMNAGAAMAPTTSHRHTT | |
| SCHEMBL12433616 | 0.72 | SLC6A2 (0.32) | LMNAGAAMAPTTSHRHTT | |
| SCHEMBL7681834 | 0.72 | NPC1 (0.46) | LMNAGAAMAPTTSHRHTT | |
| SCHEMBL8132262 | 0.71 | TAAR1 (0.51) | GAATSHRHTTCELKDM4E | |
| SCHEMBL7688492 | 0.70 | ACHE (0.44) | LMNAGAAMAPTTSHRHTT | |
| SCHEMBL13475569 | 0.69 | HPGD (0.49) | LMNAGAAMAPTTSHRHTT | |
| SCHEMBL11871672 | 0.69 | CNR1 (0.47) | CYP1A2GPR84 | |
| SCHEMBL16493618 | 0.69 | CYP1A2 (0.40) | HPGDCYP1A2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017693-A1 | CARBOXAMIDOTHIAZOLE DERIVATIVES, PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015525-A1 | CARBOXAMIDOTHIAZOLE DERIVATIVES, PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 1999-04-01 | — | — | WO | disclosed |