Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LDLR | P01130 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681834 | 0.94 | NPC1 (0.46) | ACHEHTR4TSHRLMNAGAA | |
| SCHEMBL7688492 | 0.91 | ACHE (0.44) | ACHEHTR4TSHRLMNAGAA | |
| SCHEMBL2482136 | 0.85 | NPC1 (0.50) | ACHEHTR4LMNANPC1RAB9A | |
| SCHEMBL7682170 | 0.85 | NPC1 (0.50) | ACHEHTR4LMNANPC1RAB9A | |
| SCHEMBL2481231 | 0.84 | NPC1 (0.48) | ACHEHTR4TSHRNPC1RAB9A | |
| SCHEMBL19441890 | 0.75 | HPGD (0.43) | ACHEHTR4LMNANPC1RAB9A | |
| SCHEMBL8160657 | 0.74 | LMNA (0.44) | TSHRLMNAGAAMAPTHTT | |
| SCHEMBL6703732 | 0.74 | HTR4 (0.58) | ACHEHTR4TSHRNPC1RAB9A | |
| SCHEMBL19441888 | 0.74 | HPGD (0.44) | ACHEHTR4NPC1RAB9AHPGD | |
| SCHEMBL27598401 | 0.72 | HTR4 (0.48) | ACHEHTR4TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |