Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375454 | 1.00 | LMNA (0.38) | LMNACYP2C19LAP3FDPSCYP3A4 | |
| SCHEMBL8376451 | 1.00 | LMNA (0.38) | LMNACYP2C19LAP3FDPSCYP3A4 | |
| SCHEMBL8375428 | 0.80 | ALDH1A1 (0.36) | LMNACYP2C19 | |
| SCHEMBL8376426 | 0.80 | ALDH1A1 (0.36) | LMNACYP2C19 | |
| SCHEMBL8153842 | 0.80 | ALDH1A1 (0.36) | LMNACYP2C19 | |
| SCHEMBL8156685 | 0.69 | LMNA (0.53) | LMNACYP2C19LAP3FDPSCYP3A4 | |
| SCHEMBL8156120 | 0.69 | LMNA (0.53) | LMNACYP2C19LAP3FDPSCYP3A4 | |
| SCHEMBL8160583 | 0.69 | LMNA (0.53) | LMNACYP2C19LAP3FDPSCYP3A4 | |
| SCHEMBL8156116 | 0.65 | LMNA (0.41) | LMNACYP2C19 | |
| SCHEMBL8153378 | 0.65 | LMNA (0.41) | LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000510455-A | — | — | 2000-08-15 | — | — | JP | claimed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | claimed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | disclosed |