Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376426 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNACYP2C19 | |
| SCHEMBL8153842 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNACYP2C19 | |
| SCHEMBL8373259 | 0.82 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8375454 | 0.80 | LMNA (0.38) | LMNACYP2C19 | |
| SCHEMBL8161122 | 0.80 | LMNA (0.38) | LMNACYP2C19 | |
| SCHEMBL8376451 | 0.80 | LMNA (0.38) | LMNACYP2C19 | |
| SCHEMBL8376565 | 0.79 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8376417 | 0.79 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8153898 | 0.79 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL28708415 | 0.69 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997039756-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | TROPONWERKE GMBH & CO. KG (DE) | 1997-10-30 | — | — | WO | disclosed |