Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1731137 | 0.81 | ALDH1A1 (0.62) | KMT2ANPC1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL5097172 | 0.79 | KDM4E (0.58) | MEN1KMT2ANPC1KDM4ECYP1A2 | |
| SCHEMBL28329030 | 0.78 | ALDH1A1 (0.58) | KMT2AKDM4ECYP1A2CYP2C19CYP2D6 | |
| SCHEMBL7435213 | 0.78 | KDM4E (0.66) | MEN1KMT2ANPC1KDM4ECYP1A2 | |
| SCHEMBL14176213 | 0.78 | KDM4E (0.57) | MEN1KMT2ANPC1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL5097168 | 0.78 | KDM4E (0.57) | MEN1KMT2ANPC1KDM4ECYP1A2 | |
| SCHEMBL13475490 | 0.77 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10488011 | 0.76 | SMN1; SMN2 (0.46) | MEN1KMT2ANPC1KDM4EGAA | |
| SCHEMBL7759533 | 0.75 | POLB (0.58) | MEN1KMT2ANPC1KDM4ECYP1A2 | |
| SCHEMBL28327817 | 0.75 | KDM4E (0.50) | MEN1KMT2AKDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071946-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM, SLEEP DISORDERS, CIRCADIAN RHYTHM DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-06-06 | — | — | US | disclosed |
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | disclosed |