Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | NAMPT | P43490 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PTAFR | P25105 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406336 | 0.84 | LMNA (0.72) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL1161997 | 0.82 | NAMPT (0.75) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL8173946 | 0.81 | NAMPT (0.77) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL2984197 | 0.80 | NAMPT (0.72) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL6258710 | 0.78 | NPC1 (0.60) | SMN1; SMN2 | |
| SCHEMBL10076246 | 0.77 | TRPV1 (0.74) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL5257811 | 0.77 | LMNA (0.72) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL6569317 | 0.77 | LMNA (0.72) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL8327425 | 0.77 | PTGER1 (0.61) | TRPV1ALDH1A1NAMPTHTTLMNA | |
| SCHEMBL1568226 | 0.77 | ALDH1A1 (0.72) | TRPV1ALDH1A1NAMPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057345-A | ANTAGONISTS OF THE PAIN ENHANCING EFFECTS OF E-TYPE PROSTAGLANDINS; USED IN PAIN RELIEF | ZENECA LIMITED (GB) | 2000-05-02 | — | — | US | claimed |