Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577616 | 0.83 | DAO (0.48) | MAPK14PLA2G10PLA2G2APLA2G5EPHX1 | |
| SCHEMBL10968313 | 0.77 | MAPK14 (0.46) | GRIN2BMAPK14TRPM8MRGPRX4PIM1 | |
| SCHEMBL1695580 | 0.76 | SIRT2 (0.48) | PLA2G10PLA2G2APLA2G5KMT2AFFAR1 | |
| SCHEMBL7071749 | 0.76 | CHEK1 (0.41) | EPHX1MRGPRX4KMT2APIM1EPHX2 | |
| SCHEMBL4517767 | 0.75 | BCAT2 (0.51) | PLA2G10PLA2G2APIM1FFAR1FFAR4 | |
| SCHEMBL6518415 | 0.75 | CHEK1 (0.49) | EPHX1KMT2APIM1EPHX2MAPK8 | |
| SCHEMBL15676699 | 0.75 | RAB9A (0.48) | KMT2ASIRT2 | |
| Trifluoroacetic Acid SCHEMBL15568420 | 0.75 | ALDH1A1 (0.51) | KMT2AFFAR1SIRT2 | |
| SCHEMBL1690120 | 0.74 | RAB9A (0.46) | EPHX1KMT2ASIRT2 | |
| SCHEMBL14039560 | 0.74 | NPC1 (0.40) | KMT2ASIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |