Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.53 |
| ▸ | CBR1 | P16152 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenclofenac SCHEMBL25161 | 0.89 | CHRM1 (1.00) | CHRM1CXCL8TDP1TTRFFAR1 | |
| Fenclofenac SCHEMBL28279765 | 0.89 | CHRM1 (1.00) | CHRM1CXCL8TDP1TTRFFAR1 | |
| Fenclofenac SCHEMBL29438086 | 0.89 | CHRM1 (1.00) | CHRM1CXCL8TDP1TTRFFAR1 | |
| Fenclofenac SCHEMBL30509659 | 0.89 | CHRM1 (1.00) | CHRM1CXCL8TDP1TTRFFAR1 | |
| Fenclofenac SCHEMBL9692633 | 0.88 | CHRM1 (0.97) | CHRM1CXCL8TDP1TTRFFAR1 | |
| SCHEMBL11574819 | 0.84 | CHRM1 (0.58) | CHRM1CXCL8TDP1FFAR1SLC6A2 | |
| SCHEMBL7400584 | 0.83 | CHRM1 (0.65) | CHRM1CXCL8FFAR1MAPTLMNA | |
| SCHEMBL11089474 | 0.82 | CHRM1 (0.76) | CHRM1CXCL8TDP1TTRFFAR1 | |
| SCHEMBL12160339 | 0.81 | CHRM1 (0.59) | CHRM1TDP1TTRFFAR1SLC6A2 | |
| SCHEMBL3870178 | 0.80 | HSD17B10 (0.68) | CHRM1TDP1TTRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007501-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999010310-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |