Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81658 | 1.00 | PTGS1 (0.55) | PTGS1PTGS2ALOX5ALDH1A1CYP3A4 | |
| SCHEMBL9281030 | 0.85 | ALDH1A1 (0.59) | PTGS1ALDH1A1CYP3A4RECQLFBP1 | |
| SCHEMBL9272281 | 0.85 | ALDH1A1 (0.59) | PTGS1ALDH1A1CYP3A4RECQLFBP1 | |
| SCHEMBL7643195 | 0.85 | PTGS1 (0.51) | PTGS1PTGS2ALOX5TP53TDP1 | |
| SCHEMBL8442071 | 0.82 | TP53 (0.52) | PTGS1PTGS2ALOX5TP53TDP1 | |
| Cinnamic Alcohol SCHEMBL27980025 | 0.82 | PAM (0.48) | PTGS1PTGS2ALOX5ALDH1A1CYP3A4 | |
| SCHEMBL8442069 | 0.82 | TP53 (0.52) | PTGS1PTGS2ALOX5TP53TDP1 | |
| SCHEMBL19227545 | 0.82 | TP53 (0.52) | PTGS1PTGS2ALOX5TP53TDP1 | |
| SCHEMBL1795132 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2ALOX5ALDH1A1TP53 | |
| SCHEMBL21847980 | 0.80 | PTGS1 (0.69) | PTGS1PTGS2ALOX5ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947754-B | Use of bidentate phosphite ligands in C-F bond building reactions | 郑州大学 | 2021-02-26 | — | — | CN | claimed |
| CN-108993600-B | Use of bidentate phosphite ligands in C-B bond building reactions | 郑州大学 | 2021-01-22 | — | — | CN | claimed |
| CN-108993600-A | Application of the bidentate phosphite ester ligand in the building reaction of C-B key | 郑州大学 | 2018-12-14 | — | — | CN | claimed |
| CN-108947754-A | Application of the bidentate phosphite ester ligand in the building reaction of C-F key | 郑州大学 | 2018-12-07 | — | — | CN | claimed |
| US-4021411-A | Production of high molecular weight α,β-unsaturated aldehydes | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | claimed |
| CN-113429249-B | Method for synthesizing chiral 4-hydroxy amino acid derivative | 陕西师范大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-113429249-A | Method for synthesizing chiral 4-hydroxy amino acid derivative | 陕西师范大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-110015947-B | Method for synthesizing unsaturated primary alcohol | 南京理工大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-111233760-B | Synthetic method of 2, 4-diaryl quinoline compound | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-113135816-A | Method for synthesizing photoactive bromohydrin compound | 常州大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-108947754-B | Use of bidentate phosphite ligands in C-F bond building reactions | 郑州大学 | 2021-02-26 | — | — | CN | disclosed |
| CN-108993600-B | Use of bidentate phosphite ligands in C-B bond building reactions | 郑州大学 | 2021-01-22 | — | — | CN | disclosed |
| EP-1732887-A1 | 1-(1H-INDOL-1-YL)-3-(4-METHYLPIPERAZIN-1-YL)-1-PHENYL PROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE NOREPINEPHRINE (NE) AND THE SEROTONINE (5-HT) ACTIVITY AND THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | Wyeth (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097744-A1 | 1-(1H-INDOL-1-YL)-3-(4-METHYLPIPERAZIN-1-YL)-1-PHENYL PROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE NOREPINEPHRINE (NE) AND THE SEROTONINE (5-HT) ACTIVITY AND THE MONOAMINE REUPTAKE FOR THE TREATMENT OF VASOMOTOR SYMPTOMS (VMS) | WYETH (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050222148-A1 | Phenylaminopropanol derivatives and methods of their use | WYETH (US) | 2005-10-06 | — | — | US | disclosed |
| US-4058536-A | Production of high molecular weight α,β-unsaturated aldehydes | BASF AKTIENGESELLSCHAFT (DT) | 1977-11-15 | — | — | US | disclosed |
| US-4021411-A | Production of high molecular weight α,β-unsaturated aldehydes | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-3965193-A | Production of high molecular weight α,β-unsaturated aldehydes | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-06-22 | — | — | US | disclosed |
| US-3954804-A | Production of high molecular weight unsaturated ketones | BASF AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
| US-3932462-A | Manufacture of unsaturated ketones | BASF AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222148-A1 | Phenylaminopropanol derivatives and methods of their use | PAH, PNMT, COMT | PTGS1 367/4885PTGS2 527/4885ALOX5 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.