Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159300 | 0.82 | FDPS (1.00) | FDPSLMNACFTRGOPCHIF1A | |
| SCHEMBL24052074 | 0.76 | LMNA (0.55) | FDPSLMNAKDM4EHTTRAB9A | |
| SCHEMBL8159782 | 0.76 | FDPS (0.60) | FDPSLMNAKDM4EHTTRAB9A | |
| SCHEMBL5366533 | 0.75 | FDPS (0.59) | FDPSLMNARAB9ACFTRGOPC | |
| SCHEMBL20385720 | 0.75 | FDPS (0.77) | FDPSLMNARAB9ACFTRGOPC | |
| SCHEMBL3831616 | 0.72 | HTT (0.52) | FDPSLMNAKDM4EHTTRAB9A | |
| SCHEMBL27658618 | 0.72 | KDM4E (0.52) | FDPSLMNAKDM4EHTTRAB9A | |
| SCHEMBL3831614 | 0.72 | HTT (0.52) | FDPSLMNAKDM4EHTTRAB9A | |
| SCHEMBL8171356 | 0.71 | FDPS (0.69) | FDPSLMNAHTTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL1471266 | 0.71 | HTT (0.51) | FDPSLMNAKDM4EHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563107-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | claimed |
| EP-0563107-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| US-5393748-A | Treating bone disorders, Paget* s disease, calcium metabolism disorders | LEIRAS OY (FI) | 1995-02-28 | — | — | US | disclosed |