Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894550 | 0.90 | KEAP1 (0.46) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL14611610 | 0.82 | MME (0.41) | HDAC3HDAC4HDAC1SMN1; SMN2HDAC7 | |
| SCHEMBL31512109 | 0.82 | HDAC3 (0.68) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL2878880 | 0.82 | HDAC3 (0.68) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL10882347 | 0.80 | ALDH1A1 (0.55) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL16710893 | 0.80 | PTPN1 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL879179 | 0.79 | HDAC3 (0.59) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL7442231 | 0.79 | LMNA (0.37) | HDAC3HDAC4HDAC1SMN1; SMN2HDAC7 | |
| SCHEMBL17447915 | 0.78 | HDAC3 (0.57) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL22826566 | 0.77 | MAPT (0.67) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048852-A | BACTERICIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |