Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 5/20 | 0.47 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171324 | 1.00 | TYMS (0.47) | TYMSTYMPTK2TK1 | |
| SCHEMBL8166332 | 0.86 | TYMS (0.47) | TYMSTYMPTK2TK1 | |
| SCHEMBL6044983 | 0.86 | TK2 (0.59) | TYMSTYMPTK2TK1 | |
| SCHEMBL8159110 | 0.85 | TYMS (0.46) | TYMSTYMPTK2TK1 | |
| SCHEMBL8510099 | 0.84 | TK2 (0.52) | TYMSTYMPTK2TK1 | |
| SCHEMBL8650972 | 0.84 | TK2 (0.52) | TYMSTYMPTK2TK1 | |
| SCHEMBL10492848 | 0.84 | TYMS (0.47) | TYMSTYMP | |
| SCHEMBL7703578 | 0.82 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL3341208 | 0.82 | TYMS (0.56) | TYMSTYMP | |
| SCHEMBL3341212 | 0.82 | TYMS (0.56) | TYMSTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6031086-A | HAVING DIMINISHED CHARGE BUT UNDIMINISHED ABILITY TO COMPLEX WITH NATURAL DNA AT LOW IONIC STRENGTHS; PREPARED BY REPLACING NATURAL NUCLEOTIDES WITH UNNATURAL ZWITTERIONIC NUCLEOTIDES; MEMBRANE PERMEABLE AND NUCLEASE RESISTANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-02-29 | — | — | US | disclosed |
| US-5596091-A | DNA AND RNA FOR GENE EXPRESSION FOR DIAGNOSIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-01-21 | — | — | US | disclosed |