SCHEMBL8166391

SCHEMBL8166391

CCCCCCCCCCCCCCCc1nnc(S)n1C

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.36
SPNS2 Q8IVW8 2/20 0.35
TLR7 Q9NYK1 1/20 0.35
ALDH1A1 P00352 3/20 0.35
KCNH2 Q12809 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
CETP P11597 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
NPC1 O15118 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11512287 1.00 HSD11B1 (0.36) HSD11B1SPNS2TLR7ALDH1A1KCNH2
SCHEMBL3737700 1.00 HSD11B1 (0.36) HSD11B1SPNS2TLR7ALDH1A1KCNH2
SCHEMBL11510230 1.00 HSD11B1 (0.36) HSD11B1SPNS2TLR7ALDH1A1KCNH2
SCHEMBL4388847 0.92 ALDH1A1 (0.41) HSD11B1ALDH1A1HRH3LMNA
SCHEMBL8173050 0.81 TSHR (0.35) HSD11B1SPNS2TLR7ALDH1A1KCNH2
SCHEMBL11510482 0.79 KDM4E (0.37) HSD11B1SPNS2ALDH1A1KCNH2CETP
SCHEMBL11805405 0.79 ALDH1A1 (0.49) SPNS2TLR7ALDH1A1KCNH2CETP
SCHEMBL8062006 0.79 ALDH1A1 (0.49) SPNS2TLR7ALDH1A1KCNH2CETP
SCHEMBL9677868 0.79 ALDH1A1 (0.49) SPNS2TLR7ALDH1A1KCNH2CETP
SCHEMBL9222262 0.79 ALDH1A1 (0.49) SPNS2TLR7ALDH1A1KCNH2CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6074813-A SILVER HALIDE PHOTOSENSITIVE MATERIAL FOR EMULSION LAYERS FUJI PHOTO FILM, CO., LTD. (JP) 2000-06-13 US disclosed