Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985928 | 0.98 | KDM4E (0.38) | KDM4EGAAAPOBEC3GALDH1A1HSD11B1 | |
| SCHEMBL8173050 | 0.87 | TSHR (0.35) | ALDH1A1HSD11B1SPNS2NPC1KCNH2 | |
| SCHEMBL6743293 | 0.82 | ALDH1A1 (0.38) | KDM4EGAAALDH1A1NPC1LMNA | |
| SCHEMBL3737700 | 0.79 | HSD11B1 (0.36) | ALDH1A1HSD11B1SPNS2NPC1KCNH2 | |
| SCHEMBL8166391 | 0.79 | HSD11B1 (0.36) | ALDH1A1HSD11B1SPNS2NPC1KCNH2 | |
| SCHEMBL11510230 | 0.79 | HSD11B1 (0.36) | ALDH1A1HSD11B1SPNS2NPC1KCNH2 | |
| SCHEMBL11512287 | 0.79 | HSD11B1 (0.36) | ALDH1A1HSD11B1SPNS2NPC1KCNH2 | |
| SCHEMBL6744575 | 0.79 | LMNA (0.36) | KDM4EALDH1A1KMT2ALMNATSHR | |
| SCHEMBL10480375 | 0.78 | NPC1 (0.56) | ALDH1A1NPC1CYP19A1 | |
| SCHEMBL10480378 | 0.78 | NPC1 (0.56) | ALDH1A1NPC1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |