Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 6/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185888 | 0.79 | IDO1 (0.40) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL7181071 | 0.77 | TSHR (0.45) | TRPV6ORAI1ORAI2ORAI3ALDH1A1 | |
| SCHEMBL25456150 | 0.69 | PDE2A (0.35) | MGLL | |
| SCHEMBL19050630 | 0.66 | TRPV6 (0.53) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| O-Xylene SCHEMBL26132789 | 0.64 | TSHR (0.50) | MGLLRAPGEF4ALDH1A1TSHRGAA | |
| SCHEMBL20817224 | 0.64 | IDO1 (0.34) | MGLLTACR1IDO1TDO2RAPGEF4 | |
| SCHEMBL28994175 | 0.63 | TSHR (0.43) | ORAI1ORAI2ORAI3ALDH1A1TSHR | |
| SCHEMBL27097621 | 0.62 | RAPGEF4 (0.41) | TRPV6ORAI1ORAI2ORAI3MGLL | |
| SCHEMBL25456124 | 0.61 | RAPGEF4 (0.37) | TACR1P2RX1IDO1RAPGEF4 | |
| SCHEMBL20817222 | 0.61 | CES2 (0.41) | TRPV6ORAI1ORAI2ORAI3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003753-A1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | Basell Polyolefine GmbH (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006414-A1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | TARGOR GMBH (DE) | 1999-02-11 | — | — | WO | disclosed |