Styrene

Styrene

SCHEMBL8167241

C=C(c1ccccc1)P(=O)(O)O.C=Cc1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.41
PTK2B Q14289 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
AKT1 P31749 1/20 0.39
HDAC2 Q92769 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
LMNA P02545 2/20 0.36
AKR1C1 Q04828 1/20 0.36
PLIN1 O60240 1/20 0.36
BCHE P06276 1/20 0.36
MAPT P10636 1/20 0.36
TNFRSF1A P19438 1/20 0.36
ACHE P22303 1/20 0.36
MAOB P27338 1/20 0.36
RECQL P46063 1/20 0.36
PLIN5 Q00G26 1/20 0.36
CYP1B1 Q16678 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95085 0.86 L3MBTL1 (0.48) ALDH1A1TSHRALOX15PTK2BL3MBTL1
Acrylic Acid SCHEMBL11024012 0.83 AKT1 (0.50) ALDH1A1TSHRALOX15PTK2BL3MBTL1
Styrene SCHEMBL207126 0.82 ALDH1A1 (0.70) ALDH1A1TSHRALOX15L3MBTL1AKT1
Styrene SCHEMBL29270383 0.80 ALDH1A1 (0.67) ALDH1A1TSHRALOX15L3MBTL1AKT1
Styrene SCHEMBL11218475 0.80 ALDH1A1 (0.67) ALDH1A1TSHRALOX15L3MBTL1AKT1
Styrene SCHEMBL25387939 0.80 ALDH1A1 (0.67) ALDH1A1TSHRALOX15L3MBTL1AKT1
Styrene SCHEMBL29270380 0.80 ALDH1A1 (0.67) ALDH1A1TSHRALOX15L3MBTL1AKT1
Styrene SCHEMBL11588624 0.80 ALDH1A1 (0.67) ALDH1A1TSHRALOX15L3MBTL1AKT1
Styrene SCHEMBL1402211 0.78 ALDH1A1 (0.64) ALDH1A1TSHRALOX15L3MBTL1AKT1
Styrene SCHEMBL28453864 0.78 ALDH1A1 (0.64) ALDH1A1TSHRALOX15L3MBTL1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0858482-B1 MISCIBLE POLYMERS BAYER ANTWERPEN NV (BE) 2000-05-10 EP disclosed
US-5905118-A ACRYLONITRILE-STYRENE COPOLYMERS WITH DIALKYLVINYL AROMATIC PHOSPHONATE BAYER ANTWERPEN S.A./N.V. (BE) 1999-05-18 US disclosed
EP-0858482-A1 MISCIBLE POLYMERS BAYER ANTWERPEN N.V. (BE) 1998-08-19 EP disclosed
WO-1997016487-A1 MISCIBLE POLYMERS BAYER ANTWERPEN S.A./N.V. (BE) 1997-05-09 WO disclosed
US-5340883-A Organic liquid absorbent compositions based on phosphonic acid-containing polymers and di- or polyamines ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-08-23 US disclosed
US-5328958-A Thermoplastic resins based on vinyl aromatic/vinyl phosphonic acid copolymers and amine-terminated polymers ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-07-12 US disclosed
US-5310808-A Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-05-10 US disclosed
US-5292817-A Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-03-08 US disclosed
US-5274050-A Forming an insoluble gel ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-12-28 US disclosed
US-5237028-A Organic liquid absorbent compositions based on phosphonic acid-containing polymers and di- or polyamines ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-08-17 US disclosed