Ethylene

Ethylene

SCHEMBL8167289

C=C.O=C(CO)Nc1nc2ccccc2s1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 5/20 0.69
SMN1; SMN2 Q16637 5/20 0.69
NFKB1 P19838 2/20 0.69
NFKB2 Q00653 2/20 0.69
RELA Q04206 2/20 0.69
POLB P06746 1/20 0.69
ALDH1A1 P00352 4/20 0.68
ACP1 P24666 1/20 0.68
NCS1 P62166 1/20 0.66
DYRK1A Q13627 2/20 0.65
ADORA1 P30542 1/20 0.65
NPC1 O15118 7/20 0.64
RAB9A P51151 7/20 0.64
MAPK1 P28482 3/20 0.64
KDM4E B2RXH2 2/20 0.64
HTT P42858 1/20 0.64
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
MAPT P10636 2/20 0.63
CHEK1 O14757 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4858014 0.84 CSNK1D (0.69) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL5313704 0.84 CSNK1D (0.69) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL7933388 0.84 HDAC3 (0.71) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL29282910 0.84 DYRK1A (0.69) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL6206186 0.84 RAB9A (0.72) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL29485043 0.84 DYRK1A (0.69) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL29485044 0.84 DYRK1A (0.69) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL25938107 0.84 CSNK1D (0.69) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL28521971 0.84 CSNK1D (0.64) CSNK1DSMN1; SMN2NFKB1NFKB2RELA
SCHEMBL29483685 0.84 CSNK1D (0.64) CSNK1DSMN1; SMN2NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6068968-A CYANINE DYE HAVING AT LEAST ONE SUBSTITUENT HAVING A THIOETHER GROUP; EXHIBITING LOW FOGGING, HIGH SENSITIVITY, AND IMPROVED STORAGE STABILITY. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
US-5763153-A CONTAINING CYANINE DYE HAVING QUINOLINE NUCLEUS AND THIOETHER SUBSTITUENT; LOW FOGGING, HIGH SENSITIVITY, IMPROVED STABILITY FUJI PHOTO FILM CO. LTD (JP) 1998-06-09 US disclosed