Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154853 | 0.86 | PTGER1 (0.46) | PTGER1CYP1A2CCR5LMNAALDH1A1 | |
| SCHEMBL8155611 | 0.86 | PTGER1 (0.46) | PTGER1CYP1A2CCR5LMNAALDH1A1 | |
| SCHEMBL8167308 | 0.86 | PTGER1 (0.54) | PTGER1CYP1A2CCR5 | |
| SCHEMBL8168199 | 0.83 | PTGER1 (0.48) | PTGER1CYP1A2CCR5LMNAALDH1A1 | |
| SCHEMBL1907786 | 0.82 | RXRA (0.53) | PTGER1CYP1A2CCR5LMNAALDH1A1 | |
| SCHEMBL8156031 | 0.82 | CCR5 (0.47) | PTGER1CYP1A2CCR5 | |
| SCHEMBL8167821 | 0.81 | PTGER1 (0.44) | PTGER1CYP1A2CCR5LMNAALDH1A1 | |
| SCHEMBL8167295 | 0.81 | PTGER1 (0.46) | PTGER1CYP1A2CCR5LMNAALDH1A1 | |
| SCHEMBL7662467 | 0.80 | CCR5 (0.45) | PTGER1CYP1A2CCR5LMNAALDH1A1 | |
| SCHEMBL8163403 | 0.79 | PTGER1 (0.45) | PTGER1CYP1A2CCR5LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773930-B1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LTD (GB) | 2000-10-11 | — | — | EP | claimed |