SCHEMBL8167343

SCHEMBL8167343

CC[Zr](C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21)C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
PTPN1 P18031 1/20 0.33
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
HTR7 P34969 2/20 0.32
SLC6A4 P31645 6/20 0.32
HTR1A P08908 1/20 0.32
HTR2B P41595 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
DRD2 P14416 1/20 0.32
ALDH1A1 P00352 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CYP2A6 P11509 1/20 0.32
DHFR P00374 1/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A3 Q01959 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8679843 0.85 CYP11B2 (0.35) CA12CA1CA2CA9PTPN1
SCHEMBL4060837 0.83 CA12 (0.33) CA12CA1CA2CA9PTPN1
SCHEMBL7209110 0.82 PDCD1 (0.35) HTR7HTR1AHTR2BTMEM97SIGMAR1
SCHEMBL8710096 0.81 PPARG (0.33) PTPN1SLC6A4ALDH1A1L3MBTL1SLC6A2
SCHEMBL8678773 0.81 ALDH1A1 (0.32) CA12CA1CA2CA9PTPN1
SCHEMBL3676185 0.81 ALDH1A1 (0.33) CA12CA1CA2CA9PTPN1
Hydrochloric Acid SCHEMBL3691034 0.80 ALDH1A1 (0.33) CA12CA1CA2CA9PTPN1
Hydrochloric Acid SCHEMBL339000 0.80 ALDH1A1 (0.32) CA12CA1CA2CA9PTPN1
Hydrochloric Acid SCHEMBL7211657 0.80 CA12 (0.34) CA12CA1CA2CA9PTPN1
Fluoride SCHEMBL1131272 0.80 ALDH1A1 (0.33) CA12CA1CA2CA9PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062219-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-12-27 EP claimed
WO-1999046270-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1999-09-16 WO claimed
EP-0775148-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-05-28 EP claimed
WO-1996004290-A1 BISCYCLOPENTADIENYL DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-02-15 WO claimed
EP-1062219-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-12-27 EP disclosed
EP-0968158-A1 METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM Basell Polyolefine GmbH (DE) 2000-01-05 EP disclosed
WO-1999046270-A1 INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES THE DOW CHEMICAL COMPANY (US) 1999-09-16 WO disclosed
WO-1998040331-A1 PREPARATION OF PREPARING SUBSTITUTED INDANONES TARGOR GMBH (DE) 1998-09-17 WO disclosed