Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.32 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.31 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.30 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.30 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575783 | 0.95 | ALDH1A1 (0.31) | ALDH1A1MAPTHPGDPKMHSD17B10 | |
| Hydrochloric Acid SCHEMBL3206726 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7938954 | 0.88 | — | — | |
| SCHEMBL6055431 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL4593404 | 0.86 | KDM4E (0.37) | ALDH1A1MAPTHPGDPKMHSD17B10 | |
| Hydrochloric Acid SCHEMBL6903228 | 0.86 | KDM4E (0.37) | ALDH1A1MAPTHPGDPKMHSD17B10 | |
| Hydrochloric Acid SCHEMBL3735008 | 0.86 | ENPP3 (0.30) | CA12CA1CA2CA9 | |
| SCHEMBL5614147 | 0.85 | KDM4E (0.38) | ALDH1A1MAPTHPGDPKMHSD17B10 | |
| SCHEMBL5982706 | 0.85 | CES1 (0.34) | ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL5604464 | 0.84 | SLC6A4 (0.32) | ALDH1A1MAPTHPGDKDM1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129683-A1 | POLYMERIZATION CATALYSTS AND METHOD FOR PRESERVATION OF SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-24 | — | — | US | claimed |
| WO-2025120451-A1 | TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND PREPARATION METHOD OF OLEFIN POLYMER USING THE SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2025-06-12 | — | — | WO | disclosed |
| US-10793652-B2 | Solid PMAO composition and method for producing same | TOSOH FINECHEM CORPORATION (JP) | 2020-10-06 | — | — | US | disclosed |
| EP-1661921-B1 | Synthetic lubricating oil and lubricating oil composition thereof | MITSUI CHEMICALS INC (JP) | 2019-07-17 | — | — | EP | disclosed |
| US-20190153127-A1 | SOLID PMAO COMPOSITION AND METHOD FOR PRODUCING SAME | TOSOH FINECHEM CORPORATION (JP) | 2019-05-23 | — | — | US | disclosed |
| US-10246531-B2 | Production method for olefin-based polymer, olefin polymerization catalyst, and olefin-based polymer | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
| EP-3441406-A1 | SOLID PMAO COMPOSITION AND METHOD FOR PRODUCING SAME | Tosoh Finechem Corporation (JP) | 2019-02-13 | — | — | EP | disclosed |
| US-10150825-B2 | Production method for olefin-based polymer, and olefin polymerization catalyst | IDEMITSU KOSAN CO., LTD. (JP) | 2018-12-11 | — | — | US | disclosed |
| US-9718897-B1 | Process for the polymerization or copolymerization of an alpha olefin | LION COPOLYMER GEISMAR, LLC (US) | 2017-08-01 | — | — | US | disclosed |
| EP-3130613-A1 | PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, AND OLEFIN POLYMERIZATION CATALYST | Idemitsu Kosan Co., Ltd (JP) | 2017-02-15 | — | — | EP | disclosed |
| EP-1026177-A1 | SUPPORTED METALLOCENE CATALYST, PROCESS FOR PREPARING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMERS | CHISSO CORPORATION (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0982328-A1 | Propylene resin compositions, process for the preparation thereof, and use thereof. | TOKUYAMA CORPORATION (JP) | 2000-03-01 | — | — | EP | disclosed |
| EP-0945471-A1 | CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0942020-A1 | POLYPROPYLENE/PROPYLENE-ETHYLENE COPOLYMER COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHISSO CORPORATION (JP) | 1999-09-15 | — | — | EP | disclosed |
| EP-0942021-A1 | POLYPROPYLENE/PROPYLENE-ETHYLENE COPOLYMER COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHISSO CORPORATION (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5852143-A | Production of polyethylene using stereoisomeric metallocenes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| US-5798427-A | EXTRUDABILITY, NARROW COMONOMER DISTRIBUTION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0743327-A2 | Ethylene polymers having enhanced processability | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0743324-A2 | Production of polyethylene using stereoisomeric metallocenes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0710663-A1 | Boron-containing compound, its polymer, catalyst comprising the polymer and metallocene compound, and process for producing polyolefin | Japan Polyolefins Co., Ltd. (JP) | 1996-05-08 | — | — | EP | disclosed |