SCHEMBL8167377

SCHEMBL8167377

CC(S)C(Cc1ccccc1)C(=O)N(CC(=O)O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.53
HPGD P15428 1/20 0.41
MLYCD O95822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8167219 0.89 ACE (0.45) ACEHPGDMLYCD
SCHEMBL8159746 0.86 ACE (0.42) ACEMLYCD
SCHEMBL8159753 0.86 ACE (0.45) ACEMLYCD
SCHEMBL8167060 0.84 MLYCD (0.42) MLYCD
SCHEMBL11819600 0.81 MLYCD (0.48) MLYCD
SCHEMBL11110493 0.78 ACE (0.46) ACEHPGDMLYCD
SCHEMBL8165838 0.77 CPA3 (0.57) ACEHPGD
SCHEMBL8166520 0.77 CPA3 (0.57) ACEHPGD
SCHEMBL8170548 0.77 CPA3 (0.57) ACEHPGD
SCHEMBL9716707 0.77 MLYCD (0.61) HPGDMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6048852-A BACTERICIDES SMITHKLINE BEECHAM P.L.C. (GB) 2000-04-11 US claimed
US-6048852-A BACTERICIDES SMITHKLINE BEECHAM P.L.C. (GB) 2000-04-11 US disclosed