Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690329 | 0.86 | MLYCD (0.48) | MLYCDALDH1A1TSHRGLA | |
| SCHEMBL6047685 | 0.86 | MLYCD (0.48) | MLYCDALDH1A1TSHRGLA | |
| SCHEMBL11800781 | 0.86 | MLYCD (0.48) | MLYCDALDH1A1TSHRGLA | |
| SCHEMBL11819600 | 0.86 | MLYCD (0.48) | MLYCD | |
| SCHEMBL18765958 | 0.83 | ALDH1A1 (0.66) | MLYCDLTB4R2ALDH1A1TSHRKDM4E | |
| SCHEMBL8165475 | 0.83 | — | — | |
| SCHEMBL28110901 | 0.83 | MLYCD (0.46) | MLYCDALDH1A1TSHRGLA | |
| SCHEMBL5493790 | 0.82 | MLYCD (0.45) | MLYCDALDH1A1TSHRGLA | |
| SCHEMBL3483440 | 0.81 | LTB4R2 (0.50) | MLYCDLTB4R2ALDH1A1TSHRKDM4E | |
| SCHEMBL8074241 | 0.80 | GPR88 (0.44) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |