Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 12/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8166397 | 0.88 | FDPS (0.78) | FDPSNPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7790447 | 0.81 | FDPS (0.69) | FDPSNPC1RAB9ACA12CA1 | |
| SCHEMBL8165471 | 0.81 | FDPS (0.68) | FDPSNPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15163986 | 0.80 | FDPS (0.67) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL8166679 | 0.77 | FDPS (0.62) | FDPSNPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL15163926 | 0.76 | FDPS (0.61) | FDPSCA12MMP8CA9 | |
| SCHEMBL19468554 | 0.76 | FDPS (1.00) | FDPSNPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL13794372 | 0.75 | FDPS (0.60) | FDPSNPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7793597 | 0.75 | FDPS (0.60) | FDPSNPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL13562933 | 0.74 | FDPS (0.59) | FDPSNPC1RAB9AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563107-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | claimed |
| EP-0563107-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| EP-0563107-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011269-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | disclosed |