Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 6/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394624 | 0.86 | STING1 (0.50) | L3MBTL1STING1ALDH1A1GAAMAPT | |
| SCHEMBL8167415 | 0.84 | L3MBTL1 (0.44) | L3MBTL1STING1ALDH1A1GAAESR1 | |
| SCHEMBL8180473 | 0.81 | L3MBTL1 (0.40) | L3MBTL1STING1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8175134 | 0.80 | PPARG (0.44) | L3MBTL1ALDH1A1GAAMAPTTSHR | |
| SCHEMBL7395401 | 0.79 | L3MBTL1 (0.51) | L3MBTL1STING1ESR1CNR2 | |
| SCHEMBL8176541 | 0.76 | SERPINE1 (0.40) | L3MBTL1STING1ALDH1A1MAPTESR1 | |
| SCHEMBL7392946 | 0.76 | L3MBTL1 (0.43) | L3MBTL1STING1ALDH1A1 | |
| SCHEMBL7394439 | 0.76 | L3MBTL1 (0.43) | L3MBTL1STING1ALDH1A1 | |
| SCHEMBL7395385 | 0.75 | L3MBTL1 (0.46) | L3MBTL1STING1MAPTESR1KDR | |
| SCHEMBL8180444 | 0.73 | L3MBTL1 (0.44) | L3MBTL1STING1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048875-A | CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS | ADIR ET COMPAGNIE (FR) | 2000-04-11 | — | — | US | disclosed |