Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399212 | 0.88 | L3MBTL1 (0.43) | L3MBTL1MAPTLMNAKDRESR1 | |
| SCHEMBL8168027 | 0.87 | L3MBTL1 (0.43) | L3MBTL1KDRESR1SMN1; SMN2KDM4E | |
| SCHEMBL8167640 | 0.81 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MAPTKDRCYP1A2 | |
| SCHEMBL8174500 | 0.77 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL7391101 | 0.76 | CA12 (0.44) | L3MBTL1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7395385 | 0.76 | L3MBTL1 (0.46) | L3MBTL1MAPTLMNAKDRESR1 | |
| Ammonia Solution, Strong SCHEMBL8176215 | 0.75 | CA12 (0.43) | L3MBTL1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| Ammonia Solution, Strong SCHEMBL8176216 | 0.75 | CA12 (0.43) | L3MBTL1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8180444 | 0.74 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTLMNAKDR | |
| SCHEMBL8175134 | 0.74 | PPARG (0.44) | L3MBTL1ALDH1A1MAPTLMNAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048875-A | CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS | ADIR ET COMPAGNIE (FR) | 2000-04-11 | — | — | US | disclosed |