Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13931387 | 0.89 | PTGS2 (0.45) | PPARGLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13931388 | 0.85 | PPARG (0.42) | PPARGLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8175338 | 0.85 | PTGS2 (0.43) | PPARGPTGESALOX5PTGS2KDM4E | |
| SCHEMBL8167668 | 0.84 | PLA2G1B (0.43) | PPARGLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8165177 | 0.84 | PPARG (0.47) | PPARGMEN1ALDH1A1KMT2APTGES | |
| SCHEMBL8175786 | 0.81 | KMT2A (0.41) | LMNACYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL8171613 | 0.81 | PPARG (0.50) | PPARGPTGES2PLA2G2ATHRATHRB | |
| SCHEMBL8180895 | 0.79 | PPARG (0.52) | PPARGPTGES2F10PLA2G2A | |
| SCHEMBL8181544 | 0.79 | CYP1A2 (0.39) | LMNACYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL8174890 | 0.79 | L3MBTL1 (0.46) | LMNAMEN1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |