Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 3/20 | 0.51 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RRM2 | P31350 | 2/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21645884 | 0.96 | CTH (0.54) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL21645883 | 0.96 | CTH (0.54) | CTHFGF23ALDH1A1PLAUNOS3 | |
| Iodide SCHEMBL27462160 | 0.94 | CTH (0.53) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL23420036 | 0.79 | CTH (0.51) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL19003421 | 0.79 | CTH (0.51) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL12287558 | 0.77 | FGF23 (0.44) | CTHFGF23ALDH1A1NPC1RAB9A | |
| SCHEMBL25742795 | 0.75 | CTH (0.49) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL20597363 | 0.75 | FGF23 (0.61) | CTHFGF23ALDH1A1NPC1RAB9A | |
| SCHEMBL29402625 | 0.75 | FGF23 (0.45) | CTHFGF23ALDH1A1NPC1RAB9A | |
| SCHEMBL16712006 | 0.75 | FGF23 (0.45) | CTHFGF23ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166032-A | Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use | SYNAPSE PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 2000-12-26 | — | — | US | claimed |
| US-6166032-A | Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use | SYNAPSE PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| US-5981549-A | Method for controlling or alleviating the symptoms of respiratory disease and allergies | SYNAPSE PHARMACEUTICAL INTERNATIONAL (CA) | 1999-11-09 | — | — | US | disclosed |
| US-5916903-A | Method for reducing the effects of antineoplastic disease treatment | SYNAPSE PAHRMACEUTICALS INTERNATIONAL, INC. (CA) | 1999-06-29 | — | — | US | disclosed |
| US-5902816-A | Method for treatment of heavy metal poisoning | SYNAPSE PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 1999-05-11 | — | — | US | disclosed |
| US-5900418-A | Method for treatment of obesity | SYNAPSE PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 1999-05-04 | — | — | US | disclosed |
| US-5824684-A | Method for treating drug and alcohol addiction | SYNAPSE PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 1998-10-20 | — | — | US | disclosed |
| US-5760049-A | Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use | SYNAPSE PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 1998-06-02 | — | — | US | disclosed |