Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 3/20 | 0.54 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RRM2 | P31350 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21645884 | 1.00 | CTH (0.54) | CTHFGF23ALDH1A1PLAUNOS3 | |
| Iodide SCHEMBL27462160 | 0.98 | CTH (0.53) | CTHFGF23ALDH1A1PLAUNOS3 | |
| Iodomethane SCHEMBL8167806 | 0.96 | CTH (0.51) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL23420036 | 0.82 | CTH (0.51) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL19003421 | 0.82 | CTH (0.51) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL25742795 | 0.78 | CTH (0.49) | CTHFGF23ALDH1A1PLAUNOS3 | |
| SCHEMBL20597363 | 0.78 | FGF23 (0.61) | CTHFGF23ALDH1A1NPC1RAB9A | |
| SCHEMBL29402625 | 0.78 | FGF23 (0.45) | CTHFGF23ALDH1A1NPC1RAB9A | |
| SCHEMBL16712006 | 0.78 | FGF23 (0.45) | CTHFGF23ALDH1A1NPC1RAB9A | |
| SCHEMBL20310312 | 0.77 | CTH (0.48) | CTHFGF23ALDH1A1PLAUNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020027905-A2 | ANALOGS OF 2-PRALIDOXIME AS ANTIDOTES AGAINST ORGANOPHOSPHORUS NERVE AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-02-06 | — | — | WO | disclosed |