Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25781726 | 0.76 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2HSD11B1MAPT | |
| SCHEMBL22338746 | 0.76 | POLB (0.44) | NPC1RAB9AL3MBTL1BRD4MAPT | |
| SCHEMBL13838792 | 0.76 | HSD11B1 (0.55) | HSD11B1ALDH1A1GAA | |
| SCHEMBL2077909 | 0.75 | ALDH1A1 (0.51) | HSD11B1ALDH1A1GAA | |
| SCHEMBL8156205 | 0.75 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2HSD11B1MAPT | |
| SCHEMBL19669151 | 0.75 | TP53 (0.52) | SMN1; SMN2L3MBTL1HSD11B1MAPTALDH1A1 | |
| SCHEMBL18307633 | 0.75 | HSD11B1 (0.55) | HSD11B1ALDH1A1GAA | |
| SCHEMBL8156087 | 0.74 | TP53 (0.58) | SMN1; SMN2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL25781727 | 0.74 | CCR1 (0.53) | MAPT | |
| SCHEMBL10364979 | 0.73 | HPGD (0.53) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |