Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204639 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL2211636 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL8168377 | 0.75 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8162436 | 0.74 | TP53 (0.62) | SMN1; SMN2ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL28004758 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL8162508 | 0.70 | PLK1 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL10367016 | 0.70 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL10364979 | 0.70 | HPGD (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL10675268 | 0.69 | HSD11B1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL334957 | 0.68 | NAAA (0.73) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |