Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337927 | 0.98 | TSHR (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| SCHEMBL13303205 | 0.98 | TSHR (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| SCHEMBL13596345 | 0.93 | LMNA (0.46) | LMNATSHRNFKB1PMP22SLC22A6 | |
| SCHEMBL816963 | 0.83 | EGLN1 (0.47) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL8926737 | 0.74 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL429059 | 0.74 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL8405057 | 0.71 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL10002678 | 0.71 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2480632 | 0.71 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL20594219 | 0.71 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067625-B2 | Fluorosurfactants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-8049022-B2 | Fluorosurfactants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20090312432-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090264525-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312432-A1 | FLUOROSURFACTANTS | SGMS2, FASN, SGMS1 | LMNA 1688/4885TSHR 1160/4885NFKB1 2320/4885 |
| US-20090264525-A1 | FLUOROSURFACTANTS | FASN, FFAR3, SGMS2 | LMNA 2415/4885TSHR 754/4885NFKB1 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.