Tert-Butanol

Tert-Butanol

SCHEMBL8169028

CC(C)(C)O.O=C(O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Tert-Butanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butanol SCHEMBL6194876 1.00 ALDH1A1 (0.61)
Tert-Butanol SCHEMBL1204871 1.00 ALDH1A1 (0.61)
Tert-Butanol SCHEMBL28305217 0.95 TSHR (0.57)
Tert-Butanol SCHEMBL27435481 0.95 ALDH1A1 (0.57)
Bicarbonate SCHEMBL28154408 0.90
Tert-Butanol SCHEMBL6273948 0.86
Bicarbonate SCHEMBL9577103 0.86 ALDH1A1 (0.57)
Bicarbonate SCHEMBL9790007 0.84 CA1 (0.56)
Bicarbonate SCHEMBL8577664 0.84
Tert-Butanol SCHEMBL4348456 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106243132-A A kind of Ni metal (I) coordination compound and its preparation method and application 山西大学 2016-12-21 CN disclosed
US-6063749-A METAL STABILIZERS WITH DIALKYL CARBONATES FOR C3 TO C5 ALKYL BROMIDES GREAT LAKES CHEMICAL CORPORATION (US) 2000-05-16 US disclosed
EP-0602984-B1 Electrochemical cell ASS UNIVERSITIES INC (US) 1999-05-06 EP disclosed
US-5441831-A Redox process does not involve polymerization and depolymerization ASSOCIATED UNIVERSITIES, INC. (US) 1995-08-15 US disclosed
EP-0602984-A2 Electrochemical cell ASSOCIATED UNIVERSITIES, INC. (US) 1994-06-22 EP disclosed