Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.61 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.61 |
| ▸ | HTR3B | O95264 | 1/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548392 | 0.88 | ADRB1 (0.79) | HTR3AADRB1HTR3EHTR3BHTR3D | |
| Piperidine SCHEMBL8166500 | 0.83 | ADRB1 (0.64) | HTR3AADRB1HTR3EHTR3BHTR3D | |
| SCHEMBL82301 | 0.81 | ADRB1 (0.85) | HTR3AADRB1HTR3EHTR3BHTR3D | |
| SCHEMBL658716 | 0.81 | ADRB1 (0.85) | HTR3AADRB1HTR3EHTR3BHTR3D | |
| SCHEMBL82441 | 0.80 | ADRB1 (0.61) | ADRB1LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL81881 | 0.80 | ADRB1 (0.61) | ADRB1LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL708442 | 0.80 | ALDH1A1 (0.63) | HTR3AADRB1HTR3EHTR3BHTR3D | |
| SCHEMBL28567064 | 0.80 | ADRB1 (0.61) | ADRB1LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL708444 | 0.80 | ALDH1A1 (0.63) | HTR3AADRB1HTR3EHTR3BHTR3D | |
| Chlorobenzene SCHEMBL8165726 | 0.80 | HTR3E (0.58) | HTR3AADRB1HTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124462-A | PREPARING ARYLAMINE AND BIARYLS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-09-26 | — | — | US | disclosed |