SCHEMBL8169247

SCHEMBL8169247

CCCCC(Cl)[Si](C)(C)C(Cl)CCCC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.38
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 5/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP3A4 P08684 1/20 0.32
FDPS P14324 1/20 0.32
LMNA P02545 1/20 0.32
CA2 P00918 2/20 0.31
MAPK1 P28482 1/20 0.31
OPRM1 P35372 1/20 0.31
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
CA1 P00915 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8170969 0.82
SCHEMBL29002908 0.76 OPRM1 (0.40) DNM1ALDH1A1TSHRFDPSLMNA
SCHEMBL28402239 0.74 OPRM1 (0.44) DNM1TSHRCYP3A4LMNAOPRM1
SCHEMBL17669092 0.74 DNM1 (0.31) DNM1OPRM1
SCHEMBL17668950 0.72 DNM1 (0.33) DNM1ALDH1A1TDP1LMNACA2
SCHEMBL5575831 0.72 OPRM1 (0.42) DNM1TSHRCYP3A4LMNAOPRM1
SCHEMBL5575315 0.72 OPRM1 (0.42) DNM1TSHRCYP3A4LMNAOPRM1
SCHEMBL5575280 0.72 OPRM1 (0.42) DNM1TSHRCYP3A4LMNAOPRM1
SCHEMBL5575843 0.72 OPRM1 (0.42) DNM1TSHRCYP3A4LMNAOPRM1
SCHEMBL17668944 0.70 DNM1 (0.32) DNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6010974-A Carbon and/or silicon bridged binuclear metallocene catalyst for styrene polymerization CHEIL INDUSTRIES, INC. (KR) 2000-01-04 US disclosed