SCHEMBL8169263

SCHEMBL8169263

O=C1CCC(=O)C(OO)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8149193 0.74 POLB (0.34)
SCHEMBL19338062 0.71 THRB (0.30)
SCHEMBL7914021 0.66 TRIM24 (0.30)
SCHEMBL17867340 0.62 APEX1 (0.32)
SCHEMBL30037802 0.62 MCL1 (0.33)
SCHEMBL4598176 0.62
SCHEMBL2884597 0.62
SCHEMBL21299293 0.62
SCHEMBL6465975 0.60
SCHEMBL15659971 0.60 TLR4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5656708-A ADDING LIGNITE TO THE SOLVENT, ADDING HALIDE SALT, PEROXIDE AND HYDROPHOBIC ETHENE MONOMERS; FREE-RADICAL GRAFT POLYMERIZATION MEISTER JOHN J (US) 1997-08-12 US claimed
EP-0442508-B1 A process for making graft copolymers from lignin and vinyl monomers MEISTER JOHN J (US) 1996-12-27 EP claimed
US-5138007-A Mixture with redox initiator and halide salt MEISTER JOHN J (US) 1992-08-11 US claimed
US-5116904-A Thickener, glass transition temperature MEISTER JOHN J 1992-05-26 US claimed
WO-1992007035-A1 GRAFT COPOLYMERS OF LIGNIN (2-PROPENAMIDE)-(1-PHENYLETHENE) METHOD OF MAKING SAME AND USES THEREFORE MEISTER JOHN J (US) 1992-04-30 WO claimed
EP-0442508-A1 A process for making graft copolymers from lignin and vinyl monomers Meister, John J. (US) 1991-08-21 EP claimed
US-4931527-A WITH ACRYLAMIDE AND DIALLYLDIMETHYLAMMONIUM CHLORIDE, FOR ENHANCED OIL RECOVERY AS FLOW CONTROL AGENT MEISTER JOHN J (US) 1990-06-05 US claimed
US-6013774-A FREE RADICALLY GRAFT COPOLYMERIZING A SUBSTITUTED ETHENE OR ETHYNE ONTO LIGNIN, THEN MIXING THE GRAFTED LIGNIN WITH A POLYMER MEISTER JOHN J (US) 2000-01-11 US disclosed
US-5741875-A GRAFT POLYMER CONTAINING LIGNIN; HIGH STRENGTH; IMPACT STRENGTH; ACID RESISTANCE; ALKALI RESISTANCE; STABILITY MEISTER JOHN J (US) 1998-04-21 US disclosed
US-5656708-A ADDING LIGNITE TO THE SOLVENT, ADDING HALIDE SALT, PEROXIDE AND HYDROPHOBIC ETHENE MONOMERS; FREE-RADICAL GRAFT POLYMERIZATION MEISTER JOHN J (US) 1997-08-12 US disclosed
EP-0442508-B1 A process for making graft copolymers from lignin and vinyl monomers MEISTER JOHN J (US) 1996-12-27 EP disclosed
US-5424382-A Decomposing lignin grafted with addition polymer MEISTER JOHN J (US) 1995-06-13 US disclosed
US-5194552-A Lignin modified with acrylamide, ethylene glycol and isocyanate MEISTER JOHN J (US) 1993-03-16 US disclosed
WO-1992007035-A1 GRAFT COPOLYMERS OF LIGNIN (2-PROPENAMIDE)-(1-PHENYLETHENE) METHOD OF MAKING SAME AND USES THEREFORE MEISTER JOHN J (US) 1992-04-30 WO disclosed
EP-0442508-A1 A process for making graft copolymers from lignin and vinyl monomers Meister, John J. (US) 1991-08-21 EP disclosed
US-5037931-A Addition polymerization of acrylamide, acrylic acid, 2-methoxy ethyl ester and lignin MEISTER JOHN J 1991-08-06 US disclosed
US-4990270-A Oil recovery MEISTER JOHN J (US) 1991-02-05 US disclosed
US-4940764-A Water soluble graft copolymers of lignin and methods of making the same MEISTER JOHN J (US) 1990-07-10 US disclosed
US-4931527-A WITH ACRYLAMIDE AND DIALLYLDIMETHYLAMMONIUM CHLORIDE, FOR ENHANCED OIL RECOVERY AS FLOW CONTROL AGENT MEISTER JOHN J (US) 1990-06-05 US disclosed
US-4889902-A THICKENERS; FOAMING AGENTS; OIL RECOVERY; PLASTIC AND EXLASTOMERSI ARTICLES; GELS; MEMBRANES MEISTER JOHN J 1989-12-26 US disclosed