Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8169336 | 0.91 | ALDH1A1 (0.52) | ALDH1A1MAPTTP53CYP3A4LMNA | |
| SCHEMBL7607523 | 0.91 | ALDH1A1 (0.52) | ALDH1A1MAPTTP53CYP3A4LMNA | |
| SCHEMBL8173606 | 0.89 | ALDH1A1 (0.60) | ALDH1A1MAPTTP53CYP3A4LMNA | |
| SCHEMBL8173666 | 0.86 | LMNA (0.49) | ALDH1A1LMNASLC6A1 | |
| SCHEMBL8161909 | 0.84 | LMNA (0.61) | ALDH1A1MAPTLMNAMEN1MAPK1 | |
| Oxalic Acid SCHEMBL8173610 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNAMEN1MAPK1 | |
| SCHEMBL7605041 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNAMEN1MAPK1 | |
| SCHEMBL8173592 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTTP53CYP3A4LMNA | |
| Oxalic Acid SCHEMBL8173667 | 0.78 | SLC6A1 (0.52) | ALDH1A1LMNASLC6A1 | |
| SCHEMBL8173413 | 0.77 | LMNA (0.53) | ALDH1A1MAPTTP53CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060468-A | ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2000-05-09 | — | — | US | disclosed |
| EP-0934314-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015550-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |