Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176603 | 0.88 | NQO2 (0.48) | PLAUNQO2F2F10PRSS1 | |
| SCHEMBL8170510 | 0.80 | NQO2 (0.44) | PLAUNQO2F2F10PRSS1 | |
| SCHEMBL8169121 | 0.80 | PRSS1 (0.49) | PLAUF2F10PRSS1PRSS2 | |
| SCHEMBL6493292 | 0.78 | CNR1 (0.40) | NPC1MAPTRAB9AGFERMCL1 | |
| SCHEMBL8169720 | 0.77 | C1S (0.44) | PLAUNQO2F2PRSS1PRSS2 | |
| SCHEMBL8169108 | 0.77 | LMNA (0.48) | PLAUNQO2F10PRSS1PRSS2 | |
| SCHEMBL8174039 | 0.77 | NQO2 (0.43) | PLAUNQO2F10PRSS1PRSS2 | |
| SCHEMBL8163067 | 0.77 | PRSS1 (0.54) | PLAUNQO2F2F10NPC1 | |
| SCHEMBL8557318 | 0.77 | NQO2 (0.48) | PLAUNQO2F2F10PRSS1 | |
| SCHEMBL8176121 | 0.77 | HTT (0.39) | PLAUNQO2F2F10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |