SCHEMBL8170243

SCHEMBL8170243

c1ccc2nc3cc4cccnc4nc3cc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
MAPT P10636 5/20 0.54
GLA P06280 2/20 0.54
HPGD P15428 2/20 0.54
ACHE P22303 1/20 0.54
NQO2 P16083 2/20 0.52
NPC1 O15118 3/20 0.44
POLB P06746 3/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 2/20 0.41
HTR3A P46098 1/20 0.41
TP53 P04637 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162529 0.92 ALDH1A1 (0.58) ALDH1A1MAPTGLAHPGDACHE
Hydrazine SCHEMBL2373463 0.88 ALDH1A1 (0.54) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL14041416 0.85 ALDH1A1 (0.50) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL997757 0.83 ALDH1A1 (0.54) ALDH1A1MAPTNQO2NPC1POLB
Quinoline SCHEMBL7993280 0.83 ALDH1A1 (0.61) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL13156531 0.82 ALDH1A1 (0.46) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL13156498 0.82 NQO2 (0.60) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL20272946 0.81 ALDH1A1 (0.44) ALDH1A1MAPTNPC1POLBRAB9A
SCHEMBL29524245 0.81 ALDH1A1 (0.62) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL2386458 0.81 ALDH1A1 (0.62) ALDH1A1MAPTGLAHPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3168221-B1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE COMPRISING SAME, AND DISPLAY SAMSUNG SDI CO LTD (KR) 2023-06-28 EP disclosed
US-6110910-A ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANTIRHEUMATIC AGENTS, ANTICARCINOGENIC AGENTS DUPONT PHARMACEUTICALS (US) 2000-08-29 US disclosed
US-5874441-A TREATMENT OF AUTOIMMUNE DISEASES, INFLAMMATION DUPONT PHARMACEUTICALS COMPANY (US) 1999-02-23 US disclosed
EP-0716652-A1 CARBOCYCLIC AND HETEROCYCLIC FUSED-RING QUINOLINECARBOXYLIC ACIDS USEFUL AS IMMUNOSUPPRESSIVE AGENTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-06-19 EP disclosed
US-5428040-A Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-06-27 US disclosed
WO-1995006640-A1 CARBOCYCLIC AND HETEROCYCLIC FUSED-RING QUINOLINECARBOXYLIC ACIDS USEFUL AS IMMUNOSUPPRESSIVE AGENTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-03-09 WO disclosed