Sugi Predict

Sugi Predict / Compounds / SCHEMBL162529

SCHEMBL162529

SCHEMBL162529

c1ccc2nc3ncccc3cc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.58
▸ MAPT P10636 3/20 0.58
▸ GLA P06280 1/20 0.58
▸ HPGD P15428 1/20 0.58
▸ ACHE P22303 1/20 0.58
▸ NPC1 O15118 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.44
▸ CASP1 P29466 2/20 0.44
▸ HTR3A P46098 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ HSP90AA1 P07900 1/20 0.44
▸ HSP90AB1 P08238 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ KMT2A Q03164 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL2373463 0.96 ALDH1A1 (0.54) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL8170243 0.92 ALDH1A1 (0.54) ALDH1A1MAPTGLAHPGDACHE
Quinoline SCHEMBL7993280 0.91 ALDH1A1 (0.61) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL13156531 0.85 ALDH1A1 (0.46) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL20272946 0.84 ALDH1A1 (0.44) ALDH1A1MAPTNPC1POLBRAB9A
SCHEMBL832575 0.84 ALDH1A1 (0.48) ALDH1A1MAPTNPC1POLBRAB9A
SCHEMBL29384237 0.84 ALDH1A1 (0.48) ALDH1A1MAPTNPC1POLBRAB9A
SCHEMBL13156534 0.83 NPC1 (0.48) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL997757 0.83 ALDH1A1 (0.54) ALDH1A1MAPTNPC1POLBRAB9A
SCHEMBL13156503 0.80 ALDH1A1 (0.52) ALDH1A1MAPTGLAHPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 883 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071498-A Organic electroluminescent material and device 环球展览公司 2026-05-22 — — CN claimed
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 — — US claimed
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 — — US claimed
US-12497560-B2 Organic light-emitting device and apparatus including organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2025-12-16 — — US claimed
EP-4648800-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 — — EP claimed
EP-4648801-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 — — EP claimed
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 — — EP claimed
CN-120051299-A Vaccine 葛兰素史克生物有限公司 2025-05-27 — — CN claimed
US-20250115680-A1 PTK7 BINDING AGENTS, CONJUGATES THEREOF AND METHODS OF USING THE SAME WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-04-10 — — US claimed
CN-119350325-A Benzonaphthalazin-5-one derivative and preparation method and application thereof 宁夏医科大学 2025-01-24 — — CN claimed
WO-1993007145-A1 METHOD FOR PREPARING BENZO[b]NAPHTHYRIDINES LABORATOIRE ROGER BELLON (FR) 1993-04-15 — — WO claimed
EP-0536035-A1 1,8-Benzonaphthyridine derivatives and antimicrobial compositions LABORATOIRE ROGER BELLON (FR) 1993-04-07 — — EP claimed
EP-0528922-A1 NEW SULFONYL COMPOUNDS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1993-03-03 — — EP claimed
WO-1991017991-A1 NEW SULFONYL COMPOUNDS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1991-11-28 — — WO claimed
US-5053509-A Microbiocides; AIDS LABORATOIRE ROGER BELLON (FR) 1991-10-01 — — US claimed
EP-0431991-A1 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them Société anonyme dite: LABORATOIRE ROGER BELLON (FR) 1991-06-12 — — EP claimed
US-5004745-A Benzo[1,8]naphthyridine derivatives, their preparation and the compositions which contain them LABORATOIRE ROGER BELLON (FR) 1991-04-02 — — US claimed
US-4990515-A Chemical intermediates RHONE-POULENC SANTE (FR) 1991-02-05 — — US claimed
US-4970213-A Benzo(1,8)naphthyridine derivatives as intermediates RHONE-POULENC SANTE (FR) 1990-11-13 — — US claimed
EP-0379412-A1 1,8-Benzonaphthyridine derivatives, their preparation and compositions containing them Société anonyme dite: LABORATOIRE ROGER BELLON (FR) 1990-07-25 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME CSGALNACT1, SLC43A1, OSTC ALDH1A1 990/4885MAPT 2416/4885GLA 2185/4885
US-20250115680-A1 PTK7 BINDING AGENTS, CONJUGATES THEREOF AND METHODS OF USING THE SAME PTK2B, PTK2, LTK ALDH1A1 4606/4885MAPT 3765/4885GLA 4269/4885
US-12497560-B2 Organic light-emitting device and apparatus including organic light-emitting device CRY1, CYBA, CRY2 ALDH1A1 28/4885MAPT 879/4885GLA 622/4885
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME MGAT3, GALE, GPI ALDH1A1 1087/4885MAPT 1457/4885GLA 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.